Metoprolol (me TOE pro lol) is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to treat heart attacks. Metoprolol is also used sometimes to prevent migraine headaches and to treat irregular heartbeat and movement disorders caused by medications for mental illness.
Metoprolol comes as a tablet to take by mouth. The regular tablet is usually taken once or twice a day with meals or immediately after meals. To help you remember to take Metoprolol, take it around the same time every day. Take Metoprolol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Metoprolol controls high blood pressure and angina but does not cure them. It may take a few weeks before you feel the full benefit of Metoprolol. Continue to take Metoprolol even if you feel well.
Tell your doctor if any of these symptoms are severe or do not go away: dizziness or lightheadedness; tiredness, depression, upset stomach, dry mouth, stomach pain, vomiting, gas or bloating; heartburn, constipation, rash or itching; cold hands and feet; runny nose.
Other less serious side effects are more likely to occur, such as: vomiting; decreased sex drive, impotence, or difficulty having an orgasm; sleep problems (insomnia); tired feeling; or anxiety, nervousness.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects: slow or uneven heartbeats; feeling light-headed, fainting; feeling short of breath, even with mild exertion; swelling of your ankles or feet; nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); depression; or cold feeling in your hands and feet.
Symptoms of a Metoprolol overdose may include uneven heartbeats, difficulty breathing or swallowing; shortness of breath, swelling of the hands, feet, ankles, or lower legs; bluish-colored fingernails, dizziness, weakness, fainting, or seizure (convulsions). If you suspect an overdose of Metoprolol, seek medical attention immediately.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
If you need to have any type of surgery, you may need to temporarily stop using Metoprolol. Be sure the surgeon knows ahead of time that you are using Metoprolol.
Metoprolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Metoprolol.
Do not use this medication if you are allergic to Metoprolol, or if you have:
a heart problem such as heart block, sick sinus syndrome, or slow heart rate;
problems with circulation (such as Raynaud's syndrome).
Before taking Metoprolol, tell your doctor if you have:
congestive heart failure; asthma, bronchitis, emphysema; diabetes; low blood pressure; depression; liver or kidney disease; a thyroid disorder; or myasthenia gravis.
Tell your doctor if you have a slow heart rate, heart failure, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat).Your doctor may tell you not to take Metoprolol.
Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Metoprolol, call your doctor.
You should know that if you have allergic reactions to different substances, your reactions may be worse while you are using Metoprolol, and your allergic reactions may not respond to the usual doses of injectable epinephrine.
Before taking Metoprolol, tell your doctor and pharmacist if you are allergic to Metoprolol, acebutolol (Sectral), atenolol (Tenormin, in Tenoretic), betaxolol (Kerlone), bisoprolol (Zebeta, in Ziac), carvedilol (Coreg), Esmolol (Brevibloc), labetalol (Trandate), nadolol (Corgard, in Corzide), pindolol, propranolol (Inderal, Inderal LA, Innopran XL, in Inderide), sotalol (Betapace, Betapace AF, Sorine), timolol (Blocadren, in Timolide), any other medications, or any of the ingredients in Metoprolol tablets.
Before taking Metoprolol, tell your doctor if you are using:
digoxin (digitalis, Lanoxin);
cimetidine (Tagamet); diphenhydramine (Benadryl);
ranitidine (Zantac); anti-malaria medications such as chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox); medicine to treat depression or mental illness, such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), thioridazine (Mellaril), and others; an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage); a heart medication such as nifedipine (Procardia, Adalat), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpalan, Serpasil, Serpatab), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem); medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair); a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Metoprolol, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex), and others; or cold medicines, stimulant medicines, or diet pills.
If you are using any of these drugs, you may not be able to take Metoprolol, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect Metoprolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Store Metoprolol at room temperature between 68 and 77 degrees F (20-25 degrees C) away from sunlight and moisture.